The CADLIVE (Computer-Aided Design of LIVing systEms) System consists of the CADLIVE GUI Network Constructor, the Pathway Search Program for Virtual Knockout Mutants, the CADLIVE Grid Layout Program, the CADLIVE Dynamic Simulator, and the CADLIVE Metabolic Engineering Tools. The Network Constructor enables one to construct large-scale biochemical network maps. The Pathway Search Program for Virtual Knockout Mutants explores all possible pathways between two species and can be applied to a knockout mutant. The Grid Layout Program automatically layouts biochemical networks on two-dimensional squared grid. The Dynamic Simulator automatically converts biochemical network maps into dynamic models and simulates their dynamics. The Metabolic Engineering Tools are developed as elementary mode based
algorithms.
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